VIP (Vasoactive Intestinal Peptide)

Description

Research suggests the following potential benefits:

• Controls chronic inflammation: VIP regulates the body’s immune response by balancing anti- and pro-inflammatory mediators. Its ability to reduce chronic inflammation is being investigated for the treatment of autoimmune conditions such as multiple sclerosis, Crohn’s disease, and rheumatoid arthritis.
• Supports oral tolerance: In research, VIP has been shown to enhance oral tolerance, a process that prevents the immune system from overreacting to ingested substances like food.
• Aids in septic shock: By suppressing excessive inflammatory responses, VIP has been observed to prevent death in experimental models of septic shock, an acute inflammatory condition with high mortality. 

• Neuroprotection: VIP helps protect neurons from damage and encourages the growth of new neurons. It has also demonstrated neuroprotective effects in models of neurodegenerative diseases, including Alzheimer’s and Parkinson’s.
• Cognitive support: By promoting healthy blood flow to the brain and reducing neuroinflammation, VIP may support cognitive function and help with symptoms like brain fog.
• Modulates brain activity: In the hippocampus, the brain’s learning and memory center, VIP plays a key role in controlling neurotransmission and synaptic plasticity.
• Aids in nerve regeneration: VIP promotes the survival and regeneration of neurons following injury. 

• Regulates gut health: VIP is vital for maintaining the health of the gastrointestinal tract. It supports the integrity of the intestinal epithelial barrier and helps regulate the balance of gut microbiota.
• Enhances digestion: It regulates key digestive functions, including gastric acid secretion, intestinal contractions, and the release of water and enzymes from the pancreas.
• Combats intestinal inflammation: As a potent anti-inflammatory mediator, VIP contributes to gut bacterial tolerance and may be beneficial for managing inflammatory bowel diseases. 

• Vasodilation: VIP induces the relaxation of smooth muscles in blood vessels, which improves blood flow and lowers blood pressure.
• Cardiac protection: Animal studies suggest VIP may protect the heart from injury caused by cardiac ischemia (reduced blood flow).
• Respiratory support: Research shows that VIP can reduce airway inflammation and hyperresponsiveness in models of asthma, which enhances airway relaxation. 

• Metabolic regulation: VIP can transiently improve insulin sensitivity and regulate the release of insulin and glucagon from the pancreas.
• Bone health: VIP plays a role in regulating bone metabolism and has been shown to prevent chronic cartilage damage in osteoarthritis models.
• Circadian rhythm synchronization: The peptide plays a role in regulating circadian rhythms, which are crucial for maintaining the body’s internal clock